Diphenhydramine Hydrochloride + Zinc Acetate
This cream is used to temporarily relieve pain and itching associated with: insect bites, minor burns, sunburn, minor skin irritations, minor cuts, scrapes, rashes due to poison ivy, poison oak, and poison sumac, dries the oozing and weeping of poison ivy, poison oak, and poison sumac.
Local Antipruritic, Topical Antihistamines
Diphenhydramine is an antihistamine and works as a topical antiallergic and analgesic by blocking the releases of histamine at its sources. Zinc is used as a skin protectant.
Dosage & Administration
Adults & children above 2 years: Apply to the affected area 3 to 4 times daily. Before application ofcream, the skin should be clean, cool and dry. Should not have a hot shower or bath before applying. Apply the cream lightly on the skin until the cream disappears. It is important to include all skin surfaces, such as between the fingers and toes, under the nails and on the soles of the feet.
For babies under 2 years: Initially consult with the physician, if it is recommended, apply to the face, neck, ears and scalp as well, only avoiding the area immediately around the eyes and mouth. Leave cream on for at least 8 hours, before washing off. Reapply to any area that may be washed during the 8 hours treatment time (such as after washing the hands).
Masks ototoxicity produced by aminoglycosides. Increases gastric degradation of levodopa and decreases its absorption by reduction of gastric emptying. Antagonises therapeutic effects of cholinergic agents e.g. tacrine, donezepil and neuroleptics. Valerian, St. John’s wort, Kava Kava and gotu kola may increase CNS depression.
Potentially Fatal: Potentiates CNS depression with alcohol, barbiturates, analgesics, sedatives and neuroleptics. Additive antimuscarinic action with MAOIs, atropine and TCAs.
Contraindicated in individuals with a known allergy to its components, other pyrethroids or pyrethrins.
Contact dermatitis with mild erythematous vesicular lesions and papules has occasionally been reported.
Pregnancy & Lactation
In the absence of specific studies in pregnant women its use in pregnancy should only follow medical advice. However, teratogenic effects would not be anticipated. Although caution should be exercised in administration of diphenhydramine to nursing mothers, levels in breast milk following topical application are likely to be very low.
For external use only. Flammable, keep away from fire or flame. Do not use on large areas of the body with any other product containing diphenhydramine, even once taken by mouth. When using this product, avoid contact of eyes.
Store at a cool and dry place. Protect from light. Do not freeze.